Scientist - AAV Capsid Screening

Discovery Services · Oxford, Oxfordshire
Department Discovery Services
Employment Type Full-Time
Compensation Competitive Dependent on Experience

You will contribute towards internal R&D and commercial projects focused on OXGENE’s AAV Capsid Discovery platform. This is an exciting opportunity to join the newly established AAV Capsid Screening team and we are looking for individuals that are excited to be involved in the further development of this novel pipeline. This is a lab-based role and candidates should be able to work to tight timelines. The Scientist will be involved in commercial projects, which may result in shifting priorities. Candidates will have in-depth knowledge and experience in AAV virology as well as a broad array of molecular biology techniques and enthusiasm about team-work and a drive for operational excellence.


Key responsibilities:

  • Designing, recommending and ensuring the highest quality execution of experiments
  • Making recommendations for optimising procedures and processes, focusing on data integrity and accuracy
  • Troubleshooting and analysing experimental results and using this analysis to make suitable recommendations
  • Drafting patents with support from more experienced colleagues
  • Recommending appropriate publications and co-writing of papers for submission to these publications
  • Keeping up to date with relevant scientific literature and developments, appropriate to team projects and priorities
  • Supervising less experienced members of the team and supporting their training and development


Qualifications, Skills and Experience:

Essential:

  • Minimum MSc with demonstrable laboratory experience or PhD/DPhil in relevant discipline (Biology, Genetics or Virology)
  • Strong molecular biology skills, including PCR, (q)RT-PCR, transfections, flow cytometry and Western blotting
  • Experience in the fields of lentivirus or adeno-associated viruses (AAV)
  • Expertise in mammalian cell culture, including primary human cells
  • Self-motivated; demonstrated success in delivering assigned tasks according to timelines
  • Strong team playing skills (ideally in multidisciplinary teams)


Desirable:

  • Experience in a commercial/industrial setting
  • Experience using CRISPR based gene-editing approaches, or related genome engineering technologies
  • Experience in generation of standard operating procedures (SOPs)
  • Experience in using robotic liquid handling and automation systems


About OXGENE™

OXGENE, a WuXi Advanced Therapies (WuXi ATU) company, develops pioneering technologies to accelerate the discovery and biomanufacture of cell and gene therapies. We recruit only the best from across the globe to join us on our mission. We are focussed on providing our employees with a rich and rewarding work life, developing their skills sets and supporting their own personal aspirations. Our discovery technologies help pioneers advance their CAR-T, CRISPR, capsid or promoter discovery programmes. Our biomanufacturing solutions further accelerate the development and scalable manufacture of lentiviral, AAV or adenoviral vector based therapeutics.


OXGENE Benefits:

  • 25 days annual leave, increasing to 30 with service and 8 UK bank/public holidays per annual leave year and a day off on your birthday
  • Pension with salary exchange and generous employer contribution
  • Group life cover
  • Employee assistance programme
  • Private medical insurance with additional wellness benefits (as a benefit in kind)
  • Group Income Protection 


Notes to all applicants: 

To apply please visit our website and complete our application form with a copy of your CV. 


By the start of employment, the successful candidate must have, and be able to demonstrate, permission to work in the UK. Unfortunately, we are not currently able to provide sponsorship under the Skilled Worker route for candidates.


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  • Location
    Oxford, Oxfordshire
  • Department
    Discovery Services
  • Employment Type
    Full-Time
  • Compensation
    Competitive Dependent on Experience