Technician - Viral Design and Discovery

Gene Therapy · Oxford, Oxfordshire
Department Gene Therapy
Employment Type Full-Time
Minimum Experience Entry-level
Compensation £17,000 - £22,000 per annum, dependent on experience plus benefits

 


About OXGENE™

OXGENE redefines possible in mammalian cell engineering. Our technology platforms and expert solutions accelerate the discovery, development and manufacture of cell and gene therapies.

 

We address some of the most important and challenging questions in modern biology within gene therapy, antibody-based therapeutics and CRISPR / gene editing.

 

Our technologies enable precise and robust mammalian cell engineering. Our automation and informatics driven approaches mean we solve the problems that no-one else can to advance the delivery of new therapeutics.

 

Role Overview:

The candidate will provide technical support to a multi-disciplinary group of scientists and external research collaborators to develop viral gene therapy vectors. Working under the direction of the Senior Group Leader and senior members of the team, you will use the pioneering technologies developed at OXGENE to deliver research on viral design and discovery. Projects will be varied, and activities will span laboratory-based work, data collection and analysis, and presentation of research findings within the company.

 

The candidate must be able to work independently following instruction, and training as required. You will be expected to keep excellent laboratory records, and to work in a safe and responsible manner following standard operating practices and all safety guidelines.

 

We are looking for someone who is ambitious, proactive and is happy to jump in when required in what will be an exciting working environment. This post will be fully supported by the team and line management for the development and establishment of your career. 

 

Key responsibilities:

  • Support the strategic direction of the group by conducting experimental laboratory work to a high standard, including but not limited to:
    • DNA cloning with plasmid vector
    • Mammalian cell maintenance
    • Mammalian cell transfection
    • Production of viral vector stocks
    • Characterisation of viral vector stocks
  • Maintain accurate records and documentation for all procedures performed.
  • Analyse data, write reports, and present findings regularly at team meetings
  • Work to tight deadlines.
  • Actively engage in own career and skills development.
  • Keep up to date with advancements in the field.
  • To adhere strictly to established quality standards, essential for on-going activities

 

Essential Criteria:

  • BSc in relevant discipline, or equivalent higher education qualifications,
  • Experience working in a commercial/industrial environment is preferred but not essential
  • Willingness to work with viral vectors (adenovirus, lentivirus, AAV)
  • High-level attention to detail, and adherence to quality-related aspects


Desirable criteria:

  • Standard mammalian cell culture techniques and handling of both adherent and suspension cells
  • Experience in DNA cloning with plasmid vectors (restriction enzyme digestions, PCR, transformation of competent cells, preparation of DNA stocks from bacterial cultures)

  

Benefits 

  • 25 days of annual leave, rising to 30 days with service and a day off on your birthday 
  • Salary sacrifice contributory pension scheme where OXGENE will match up to 7% of salary
  • Free tea and coffee 
  • Cycle to work scheme
  • EAP including confidential and free of charge access to telephone support and counselling 
  • Private medical insurance with comprehensive cover as a benefit in kind 
  • A friendly and flexible working environment 

 

Notes to all applicants 

All applicants must be eligible to work in the UK.

Correspondence may go into your junk/spam folders so please keep an eye on this. 

This advert will close as soon as sufficient applications have been received. Please submit your application as soon as possible to avoid missing the opportunity.

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  • Location
    Oxford, Oxfordshire
  • Department
    Gene Therapy
  • Employment Type
    Full-Time
  • Minimum Experience
    Entry-level
  • Compensation
    £17,000 - £22,000 per annum, dependent on experience plus benefits